HUMAN GROWTH HORMONE (HGH)

By the time we reach the age of 30, our human growth hormone (HGH) levels are only about 20 percent of their peak levels during childhood, and after the age of 30, they continue to decline at about 12 to 15 percent per decade, and often much more. So, at the time when our bodies need HGH for repair, that is as we age, HGH is at its lowest levels.

• Fatigue
• Low Energy
• Decreased Sense of Well-Being
• Decreased Muscle Mass or Strength
• Decreased Blood Levels of IGF-1
• Poor Sleep Quality
• Increased Body Fat, Especially Around the  Waist
• Mood Swings, Anxiety, Depression 
• Feelings of Being Isolated from Other People
• Difficulty Concentrating
• Lack of Drive or Desire to Exercise
• Poor Healing or Weakened Immune System
• Reduced Bone Density and a Tendency to Have More Bone Fractures 
• Greater Sensitivity to Heat and Cold

Men can benefit from supplementing human growth hormone (HGH) with their testosterone replacement therapy, which will optimize the benefits of testosterone while adding additional health benefits.

Studies have shown that the fastest and most effective way to manage the signs and symptoms of aging, such as decreased libido, lack of energy, weight gain or difficulty losing weight, decreased mental alertness, and a weakened immune system is to boost your growth hormone levels.

Generally, there are two ways to boost levels of human growth hormone (HGH) in the body. One way is to use actual HGH and the other way is to use growth hormone releasing hormone (GHRH) like Sermorelin.

Human growth hormone promotes the growth of tissues, protein deposition, and the breakdown of subcutaneous fat stores. In the body, the actual structure of growth hormone is a sequence of 191 amino acids. It exists at especially high levels during adolescence, but as men age, levels of HGH decrease and remain in the body at a substantially lower level. 

The use of growth hormone has been increasing in popularity among aging men, due to the numerous benefits associated with its use. It stimulates growth in most body tissues, primarily due to increases in cell number rather than size. This includes skeletal muscle tissue and other body organs except for the eyes and brain. The transport of amino acids is also increased, as is the rate of protein synthesis. All these effects are mediated by IGF-1 (insulin-like growth factor), which is a highly anabolic hormone. Growth hormone also stimulates triglyceride hydrolysis in adipose tissue, usually producing notable fat loss during treatment. Fats become a more primary source of fuel that further enhances body fat loss.

Its growth promoting effects also strengthens connective tissues, cartilage, and tendons. This effect should reduce the susceptibility of injury (due to weight training) and may increase strength. 

Daily dosing is important, as HGH has a short life span in the body. Peak blood concentrations are noted quickly (2-6 hours) after injection and it is cleared from the body with a half-life of 20-30 minutes. Clearly it does not stick around exceptionally long. The effects of HGH are most pronounced when it is used for longer periods of time, often several months. Some men use it for at least four weeks when looking for fat loss. Subcutaneous injections are particularly noted for producing a localized loss of fat, requiring the injection site to be moved regularly to even out the effect.

Other medications may be required in conjunction with HGH in order to elicit the best results. The body requires increased amounts of thyroid hormones, insulin, and androgens while HGH levels are elevated (HGH therapy lowers thyroid and insulin levels). 

HGH itself has its own risks at higher doses, which are extremely rare. The most predominately adverse effect at would be acromegaly, or a noticeable thickening of the bones (notably the feet, forehead, jaw, and elbows). HGH can enlarge vital organs such as the heart and kidney. Also, it has been linked to hypoglycemia and diabetes (presumably due to its ability to induce insulin resistance). If there are any noticeable changes in bone structure, skin texture, or normal health during use, then HGH therapy should be completely stopped.

GH-RH, or Growth Hormone Releasing Hormone is a pharmaceutical compound that contains the active substance Sermorelin acetate. GHRH increases the level of growth hormone in the blood by stimulating the pituitary gland to manufacture more of this hormone. 

Originally FDA-approved for use in children, but many physicians are using it off label to optimize growth hormone levels of adult patients. Also, it does not negatively impact glucose, insulin or glucagon, luteinizing and follicle-stimulating hormones, cortisol, or thyroid levels.

During adolescence, GHRH exists at especially high levels, but as men age, levels of GHRH decline and remain in the body at a substantially lower level. 

The use of GHRH has been increasing in popularity among aging men for the same reasons they use HGH. Among other benefits, an elevated growth hormone level can elicit new muscle growth, increase fat loss, enhance energy levels, and strengthen connective tissues. Since the increased volume of human growth hormone is produced by the body’s pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by the Sermorelin stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system. Its use for adult hormone deficiency is not restricted.

In a University of Washington study consisting of 6 months treatment with daily bedtime subcutaneous injections of Sermorelin, alone or in combination with supervised exercise conditioning, IGF-I levels rose approximately 35%. As with HGH, subjects showed an increase in lean body mass and a decrease in body fat (particularly abdominal visceral fat).

Sermorelin is readily destroyed by enzymes in the digestive tract, therefore injections are the only way to administer the molecule. Sermorelin does not remain active in the bloodstream exceptionally long, having a half-life of 10-20 minutes so injections are to be given daily. Also, it should be injected subcutaneously in order to extend its release time. 

The main drawback for most patients for HGH therapy is cost. This is the reason why many patients prefer Sermorelin therapy as an alternative treatment. However, many patients prefer HGH therapy because for some, HGH therapy is more effective.

While the goal of both HGH therapy and Sermorelin therapy are the same, they achieve this goal through different means. HGH therapy involves the direct injection of HGH into your body, which increases HGH levels by adding HGH to your internal HGH that your body creates on its own. Sermorelin, on the other hand, increases HGH through stimulating your body to produce more HGH on its own. Both therapies achieve the same goal, which is the increase in HGH levels, but through different mechanisms.

Common side effects of Sermorelin include reactions at the injection site, such as pain, redness or swelling; and less than 1 percent of patients report dizziness, flushing, headache or hyperactivity.

• Increase Bone Density 
• Regenerate Nerve Tissues 
• Strengthen the Cardiovascular System 
• Strengthen the Immune System 
• Increase Muscle Mass 
• Enhance Energy Levels 
• Improve Ability to Burn Fat 
• Improve Cognition and Memory 
• Increase Sex Drive 
• Improve Bone and Mineral Density 
• Improve Recovery and Repair from Injuries

• Improved Body Composition
• Increased Bone Density
• Improved Skin Thickness and Texture
• Improved Sleep Quality 
• Increasing Energy from Fat Breakdown
• Increases Protein Synthesis
• Increases Lean Muscle through the Development of New Muscle Cells
• Decreases Body Fat and Increases Lipolysis (Fat Burning)
• Improved Libido and Sexual Performance

First Month:

• Vivid Dreams
• Better, Sounder Sleep
• Weight Loss
• Optimistic Attitude
• Improved Stamina

Second Month:

• Improved Muscle Tone
• Increased Strength
• Improved Skin Tone
• Improved Nail Growth
• Better Digestion
• Weight Loss
• Improved Vision
• Enhanced Sexual Function

Third Month:

• Improved Mental Processes
• Enhanced Productivity
• Faster Wound Healing
• Hair Re-growth
• Increased Libido
• Increased Muscle Size
• Faster Recovery from Muscle Soreness
• Greater Body Flexibility

Fourth Month:

• Heightened Improvements with All the Above
• At Times Improvements May Seem to Diminish or Plateau
• Rejuvenation is Still a Process. Benefits Should Resume with Continued Improvements

Fifth Month:

• Improved Weight Loss and Reduction of Inches
• Improved Skin Texture and Appearance
• Skin Thickening and Greater Elasticity
• Reduction of Skin Wrinkles
• Thickening of Hair with Shiny, Healthy Appearance

Sixth Month:

• Diminished Cellulite
• Improved Resistance to Colds, Flu and Other Illnesses
• Improved Eyesight
• Healing of Old Wounds
• Disappearance of Pain and Soreness