DIHEXA is a peptide variant derived from angiotensin IV. Clinical studies suggest that DIHEXA improves cognitive function as shown in animal models of disease such as Alzheimer’s. Angiotensin IV is a derivative of the vasoconstrictor angiotensin II which has been shown in animal studies to enhance acquisition, consolidation and recall of learning and memory when administered centrally or peripherally. In an assay of neurotrophic activity, DIHEXA was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor and is thought may be able to help in the repair of the brain and nerves in neurological disease.
